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Acridinium Ester (3' modification)
In molecular biology, acridinium esters are commonly used for selective labeling of proteins and nucleic acids. The acridinium ester can be bound to the corresponding target molecule (DNA, protein) by a covalent linkage. According to their highly sensitive chemiluminescence releasing in the presence of hydrogen peroxide, acridinium esters also can be used for clinical diagnostics. In contrast to radiolabeled DNA, acridinium ester linkages provide a sensitive, stable and above all safe detection method in immunoassays.