National Holiday

Due to the German national holiday "Christi Himmelfahrt" biomers.net will be closed on May, 9th, 2024. We will be back on Friday, May 10th, 2024.

Pseudouridine

Pseudouridine and N1-Methyl-Pseudouridine modified oligonucleotides.
Please contact us!
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XXL DNA

DNA oligo amounts from 10 to 500 mg, HPLC purification incl. [Read more]

Triglycine/Sortase

Sortase-mediated coupling reaction via triglycine-modified oligos

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Maleimide oligos

stable and covalent coupling with thiols
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qPCR Probes from 74,90 €

the biomers.net quencher BMN-Q1 , BMN-Q2, BMN-Q535 and BMN-Q620 as efficient alternatives to conventional dark quenchers (BHQ, BBQ, TQ) in qPCR probes [Read more]

New: Reactive modifiers

Reactive dyes and modifiers for postynthetic labeling of oligonucleotides: azide, alkyne, succinimidyl ester modifiers.
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reverse DNA modifications

reverse dA, dC, dG or dT building block from 7,50 EUR per internal modification

> Linker und Spacer
Cystein (tbuSS) (5' modification)
Die Aminothiol-Modifikation Cystein reagiert mit Cyanobenzothiazol und kann auf diese Weise effektiv verschiedene Biomoleküle miteinander verbinden.

Zum Schutz der freien reaktiven Thiolgruppe wird das Cystein in geschützter Form (Cystein mit StBu Schutzgruppe) geliefert. Vor weiteren Konjugationsschritten muss dem Kunjugationspuffer ein geeignetes Reduktionsmittel (z.B. TCEP) zugesetzt werden, um das Disulfid des Cysteins zu reduzieren und die Thiolgruppe freizusetzen.
Cysteine (tbuSS) 5' modification: 5´-Cysteine with StBu protecting group requires treatment with TCEP to obtain free, reactive cysteine.
5´-Cysteine with StBu protecting group requires treatment with TCEP to obtain free, reactive cysteine.
Back to the modification list