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RNA Oligonucleotides

RNA up to 120 bases

RNA up to 120 bases


Extra-long, synthetic RNA oligonucleotides can be synthesised now up to length of 120 bases!

- Long synthetic RNA oligonucleotides are used for a variety of applications (e.g. CRISPR)
- purification by polyacrylamide gel electrophoresis (PAGE) is already included
- 1 OD delivery amount is guaranteed has revised the options for RNA and now offers a broad range of lengths and modifications. Besides short RNAs mainly used in si-RNA-research, now offer also RNA in new scales up to a length of
120 bases
. Modifications are possible for RNAs up to 40 bases.

All RNA are purified by HPLC and will be delivered dry as single strand, if not explicitly stated otherwise.

Upon request, we also perform the annealing of two complementary RNA oligo strands for you and send you the final RNA oligo duplex. 
If you are interested, please send us the desired sequences via our Excel order form and indicate which strands should be annealed.
If you have any questions regarding the order process, please do not hesitate to contact us.

Length Synthesis scale Yield (HPLC)* Yield (PAGE)*
     2-7 Basen RM7 > 2 OD -
  RL7 > 5 OD -
     12-27 Basen RS27 > 2 OD -
     8-27 Basen RM27 > 5 OD > 1 OD
  RL27 > 10 OD > 3 OD
     28-40 Basen RS40 > 3 OD -
  RM40 > 5 OD > 1 OD
  RL40 > 10 OD > 3 OD
     41-60 Basen RM60 > 2 OD > 1 OD
  RL60 > 5 OD > 3 OD
     61-80 Basen RM80 > 2 OD > 1 OD
  RL80 > 5 OD > 3 OD
     81-100 Basen RM100 - > 1 OD
     101-120 Basen RM120 - > 1 OD

* The given yield refers to the guaranteed delivery amount in OD, the resulting values in µg or nmol depend on the length of the oligonucleotide.  
The yields are valid for mixed sequences and may vary for sequences with strong secondary structures and homopolymers.

Modified RNA

Modified RNA


RNA up to a length of 40 bases can be combined with multiple modifications, please see here an overview for possible modifications for 5´- or 3´-coupling.

  5'-modifications 3'-modifications
     Biotin yes yes
     Aminolink C6 yes yes
     Phosphate yes yes
     6-Fam yes yes
     Hex, Tet yes -
     Cyanine 3 yes -
     Tamra yes yes
     Atto-dyes yes yes
     Dyomics-dyes yes yes
     TQ2, TQ3 - yes
     BHQ-1, BHQ-2, BBQ-650 - yes
     dT dT* - yes
     Inverted end - yes
     Spacer C3 - yes

* For RNA oligonucleotides with synthesis scale RM27 and RL27 3‘ dinucleotide overhangs can be added as 3‘ modification.

XL and XXL scale RNA

XL and XXL scale for RNA oligos with 8 to 27 bases

Synthesis scale RXL27-5MG RXXL27-10MG RXXL27-25MG RXXL27-50MG
     Yield (mg) > 5 mg > 10 mg > 25 mg > 50 mg
     Yield (OD), ca. 170 OD 350 OD 850 OD  1700 OD
     Yield (µmol) 20mer, ca. 0,75 µmol 1,5 µmol 3,5 µmol 7,5 µmol

The scales are valid for unmodified RNA oligonucleotides from 8 to 27 bases with a mixed sequence. All XL and XXL RNA oligonucleotides will be HPLC purified and Maldi quality checked.

For any further information about other lengths, purifications, quality checks of oligos or modifications please contact us!