smiFISH
smiFISH - single molecule inexpensive fluorescence in situ hybridisation

A set consisting of short, target-binding, unlabelled oligo probes (OligoPool) and a double-labelled secondary probe allows extremely sensitive and specific in situ RNA detection.



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YOUR TRUSTED PARTNER FOR OLIGONUCLEOTIDES:
FAST, COMPETENT, AND RELIABLE!
Take advantage of state-of-the-art synthesis technology:
Oligonucleotides with all popular modifications at reasonable prices and with a reliable quality. Oligos for PCR, short, unmodified and quickly delivered are offered as well as high quality RNA oligos, probes for qPCR and FISH or reliable cloning oligos of (nearly) any length.
Talking about oligonucleotides:
talk to biomers.net!
Catalog Products
Oligo products:
- Random Hexamer
- Oligo dT20
- Universal Reporter
- RNase Substrate
qPCR Mastermix
Chemicals for oligonucleotide synthesis

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Distearoyl Lipid
Distearoyl lipid-oligonucleotide conjugates

- similar to the natural phospholipid structure
- increase of cell permeability
- binding of oligonucleotides to the cell surface



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biomers.net Dyes and Quenchers
Our biomers.net quencher set nearly covers the complete wavelength range of visible light:

BMN-Q460 (400-530 nm), BMN-Q535 (480-580 nm), BMN-Q590 (550-650 nm), BMN-Q620 (480-720 nm) and BMN-Q650 (550-720 nm)

biomers.net dyes: BMN-488, BMN-505, BMN-536, BMN-562
Enzymatic coupling via oligonucleotides
Protein tags such as SNAP or CLIP tag as well as HaloTag® but also the sortase-mediated linking reaction are used in various applications:

- detection
- localisation
- protein-protein interactions
- labelling, multiplex labelling (e.g. SNAP / CLIP tag)
- enzymatic coupling of different proteins or other biomolecules

Early Bird Discount
Between 6:00 and 9:30 am you‘ll get a special discount of
5 % on all your orders
!
Literature Highlights
Protocols, interesting literature and further information around the topic of oligonucleotides.

- Smart-Seq for transkriptome analysis (Picelli et al., 2014)
- Mediator Probe PCR (Faltin et al., 2012)
- MiL-FISH: Multi-labelled oligonucleotides (Schimak et al., 2015)
DNA oligos
- Unmodified oligos
- short and extra long oligos
- XXL DNA (10-500 mg)
- Sequence modifications
- Wobbles
RNA oligos
- unmodified RNA
up to 120 bases

- RNA oligo annealing
- XL and XXL RNA (5-50 mg)
- RNA modifications
- 2´-modified RNA
qPCR Probes
- Dual-Labelled Oligos
- Double Quenched Probes
- MGB Probes
- Molecular Beacons
- Scorpions
- FRET Probes
PNA oligos
- Peptide nucleic acid oligomers (PNA)
- 6-25 bases
- various modifications possible
- extreme stability
FISH Probes
- Fluorescence probes
mono-, dope-, tetraProbes
- multiProbes
- HRP probes
- smiFISH Oligo Pools
Dyes from biomers.net: BMN-488
BMN-488 has the same structure as Alexa Fluor® 488 and can be used as an excellent alternative to Fluorescein, Fam, Oregon Green 488 and Atto 488.

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